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# : 10 Aug 2008 19:15 | ویرایش بوسیله: Tiffany
Cialis Oral
Therapeutic class: PHOSPHODIESTERASE INHIBITORS
Dosage and Uses
Adult Min/Max Dose: 2.5mg/20.0mg
Common Dosages by Indication:
Erectile Dysfunction take 1 tablet (2.5 mg) by oral route once daily
take 2 tablets (5 mg) by oral route once daily
take 1 tablet (5 mg) by oral route once daily
take 2 tablets (10 mg) by oral route once daily
take 1 tablet (10 mg) by oral route once daily
take 2 tablets (20 mg) by oral route once daily
take 1 tablet (20 mg) by oral route once daily
All Labeled Uses: Erectile Dysfunction
Drug-Drug Interactions
Contraindicated Drug Combination:
Clearly contraindicated in all cases and should not be dispensed or administered to the same patient:
CGMP SPECIFIC PDE TYPE-5 INHIBITORS/NITRATES - Increased effect of the latter drug
Moderate Interaction:
Assess the risk to the patient and take action as needed.
SILDENAFIL; TADALAFIL/ITRACONAZOLE; KETOCONAZOLE - Increased effect of the former drug
SILDENAFIL; TADALAFIL/PROTEASE INHIBITORS - Adverse reaction of the former drug
CGMP SPECIFIC PDE TYPE-5 INHIBITORS/ALPHA-BLOCKERS - Increased effect of the former drug
Label Warnings
Pediatric
Warning: NOT STUDIED AGE<18YRS. NOT INDICATED FOR CHILDREN, NEONATES.
Lactation
Precaution: RAT STUDIES SUGGEST EXCRETION OCCURS. DRUG NOT INDICATED IN NURSING MOTHERS.
Pregnancy
Possibly Safe: NOT INDICATED FOR WOMEN.
Geriatric
Precaution: DOSE ADJ. FOR MILD-MOD. HEPATIC IMPAIR. & MOD-SEV. RENAL IMPAIRMENT
Adverse Effects
Most Frequent:
Abdominal Pain with Cramps, Dyspepsia, Headache Disorder
Less Frequent:
Back Pain, Cough, Flushing, Limb Pain, Myalgia, Nasal Congestion, Upper Respiratory Infection
Rare:
Abnormal Hepatic Function Tests, Angina, Anterior Ischemic Optic Neuropathy, Arthralgia, Blurred Vision, Chest Pain, Conjunctivitis, Diarrhea, Dizziness, Drowsy, Dysphagia, Dyspnea, Esophagitis, Eyelid Edema, Eye Tearing, Facial Edema, Fainting, Fatigue, Gastritis, Gastroesophageal Reflux, General Weakness, Hearing Loss, Hyperhidrosis, Hypertension, Hypesthesia, Hypotension, Insomnia, Loose Stools, Migraine, Myocardial Infarction, Nausea, Neck Pain, Ocular Pain, Orthostatic Hypotension, Pain, Palpitations, Paresthesia, Pharyngitis, Priapism, Pruritus of Skin, Retinal Blood Vessel Occlusions, Seizure Disorder, Skin Rash, Tachyarrhythmia, Tinnitus, Vertigo, Visual Changes, Visual Field Defect, Vomiting, Xerostomia
Drug-Disease Contraindications
Most Significant
Anterior Ischemic Optic Neuropathy
Significant
Acute Peptic Ulcer, Alcohol Intoxication, Aortic Valve Stenosis, Cerebrovascular Accident, Chronic Heart Failure, Exercise-induced Angina, Fibrosis of Corpus Cavernosum, Hearing Loss, Hypotension, Idiopathic Hypertrophic Subaortic Stenosis, Life-Threatening Cardiac Arrhythmias, Myocardial Infarction, Penile Angulation, Peyronie's Disease, Pigmentary Retinopathy, Priapism, Severe Autonomic Insufficiency, Severe Hepatic Disease, Severe Renal Disease, Severe Uncontrolled Hypertension, Unstable Angina Pectoris, Vision Loss
Possibly Significant
Blood Coagulation Disorder, Increased Risk of Bleeding, Leukemia, Multiple Myeloma, Seizure Disorder, Sickle Cell Disease Anemia
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